Potential role of arachidonic acid metabolites in hypoxic pulmonary vasoconstriction.

نویسندگان

  • N F Voelkel
  • M Morganroth
  • O C Feddersen
چکیده

Hypoxic vasoconstriction is important for lung ventilation/perfusion matching. The mechanism of hypoxic vasoconstriction remains elusive. Arachidonic acid is released from hypoxic tissues; possibly vasoconstricting arachidonate metabolites are involved in hypoxic pulmonary vasoconstriction. Data are presented that consider (a) lipoxygenase product(s) as "local," which could be involved in the hypoxia induced pulmonary vasoconstriction.

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عنوان ژورنال:
  • Chest

دوره 88 4 Suppl  شماره 

صفحات  -

تاریخ انتشار 1985